Publications
Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.
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The use of emerging safety biomarkers in nonclinical and clinical safety assessment – The current and future state: An IQ DruSafe industry survey
Regulatory Toxicology and Pharmacology, ISSN: 02732300
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New England Journal of Medicine, ISSN: 15334406 00284793
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Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study?
Leukemia Research, ISSN: 01452126
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An Approach to Bioactivity Assessment for Critical Quality Attribute Identification Based on Antibody-Antigen Complex Structure
Journal of Pharmaceutical Sciences, ISSN: 00223549
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Cell death pathways: intricate connections and disease implications
EMBO Journal, ISSN: 02614189
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Annals of Oncology, ISSN: 15698041 09237534
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The Lancet Respiratory Medicine, ISSN: 22132619 22132600
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Journal of Immunological Methods, ISSN: 18727905 00221759
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Journal of the American Chemical Society, ISSN: 15205126 00027863
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Nature Immunology, ISSN: 15292916 15292908
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NINJ1 mediates plasma membrane rupture during lytic cell death
Nature, ISSN: 00280836
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mAbs, ISSN: 19420870 19420862
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Ubiquitination in the regulation of inflammatory cell death and cancer
Cell Death and Differentiation, ISSN: 13509047
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American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
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Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
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Neuro-Oncology, ISSN: 15235866
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Haematologica, ISSN: 15928721
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American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
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Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients
Journal of Medicinal Chemistry,
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Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data
GigaScience,
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Venetoclax-rituximab with or without bendamustine vs bendamustine-rituximab in relapsed/refractory follicular lymphoma
Blood,
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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Nature Communications, ISSN: 20411723
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Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
npj Systems Biology and Applications,
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Journal of Patient-Reported Outcomes, ISSN: 25098020
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Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs
American Journal of Respiratory and Critical Care Medicine,
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Scientific Reports, ISSN: 20452322
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Nature Communications, ISSN: 20411723
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Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Nature Communications,
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Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Nature Communications,
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Calibrating the in vitro–in vivo correlation for OATP-mediated drug-drug interactions with rosuvastatin using static and PBPK models
Drug Metabolism and Disposition, ISSN: 00909556
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The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Nature Communications,
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Scientific Reports, ISSN: 20452322
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Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
Nature Communications,
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Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
Nature Communications,
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Advances in Therapy, ISSN: 18658652 0741238X
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Scientific Reports, ISSN: 20452322
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Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
npj Breast Cancer,
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Communications Biology, ISSN: 23993642
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Nature Communications, ISSN: 20411723
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Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
npj Breast Cancer,
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Nature Communications, ISSN: 20411723
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Drug Metabolism and Disposition, ISSN: 1521009X
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Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma
Pharmaceutical Research, ISSN: 07248741
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Development of an anti-drug antibody assay to detect anti-drug antibodies?to protein and PEG?in a PEGylated molecule
Bioanalysis,
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Communications Biology, ISSN: 23993642
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Pan-cancer population pharmacokinetics and exposure-safety and -efficacy analyses of atezolizumab in patients with high tumor mutational burden
Pharmacology Research and Perspectives,
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Phenotypic expression and clinical outcomes in a South Asian PRKAG2 cardiomyopathy cohort
Scientific Reports,
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Venetoclax Plus Rituximab in Relapsed Chronic Lymphocytic Leukemia: 4-Year Results and Evaluation of Impact of Genomic Complexity and Gene Mutations From the MURANO Phase III Study
Journal of Clinical Oncology,
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